A cell number counting factor alters cell metabolism

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چکیده

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The different components of a multisubunit cell number-counting factor have both unique and overlapping functions.

Dictyostelium aggregation streams break up into groups of 10(3) to 2 x 10(4) cells. The cells sense the number of cells in a stream or group by the level of a secreted counting factor (CF). CF is a complex of at least 5 polypeptides. When the gene encoding countin (one of the CF polypeptides) was disrupted, the cells could not sense each other's presence, resulting in non-breaking streams that ...

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ژورنال

عنوان ژورنال: Communicative & Integrative Biology

سال: 2009

ISSN: 1942-0889

DOI: 10.4161/cib.2.4.8470